This paper should prove that the phenomenon of money-laundering commonly is defined as covert, sophisticated and profitable criminal activity, whose offenders are commonly and explicitly intelligent people and always a step-ahead before the services responsible for their detection. In the work of this paper I have directed that changes in social, political and economic system contributes to dealing with real situations that as a country in transition it brings predispositions to expand money laundering in the Republic of North Macedonia and link this crime with organized crime by violates the basic tenets of the rule of law. Then, there are created serious problems in detecting and preventing the perpetrators of this crime and clarification of such a crime. New techniques that shows this type of crime are evident in the structure of offenses and offenders to turn illegal proceeds into legitimate proceeds and thus impose the need for continuous monitoring and improvement of methods for its detection. In our country, building an effective system for combating money laundering show continuous improvement and development of the capacities of all the institutions involved in the system.